Dogoxin

DIGOXIN Indication:Atrial Fibrillation Normal dot: fill up: 0.25mg every 2 hours IV or PO (max dose=1.5mg) maintenance: 0.125mg-0.375mg PO 0.125-0.25mg IV Geriatrics > 70yrs with good renal function should be smashed with 0.5mg x2 doses and maintained with 0.125mg PO once daily. The patient in this fictitious character is a 72yo who was minded(p) 0.5mg IV two hours apart (instead of the recommended half a twelve hours apart) with a maintenance dose of 0.125mg daily. Therapeutic serum suck=0.8-2ng/mL Time to peak= 1-3 hours T ½= 1.5-2 days by-line the two fill doses, the patient had a digoxin track of 1.5ng/mL. Two days, and two doses later, the patient was bradycardic and hypotensive with a digoxin level of 1.9ng/mL. digoxin was stopped and after 15 hours the digoxin level dropped to 1.2ng/mL. digoxin works by inhibiting Na+/K+ ATPase, which causes and increase in intracellular Na+ concentration and open fire running to hyperkalemia and hypercalcemia. This in turn can lead to too soon afterdepolarization, cardiac irritability, and dysrhythmias. As vagal purport increases and sympathetic tone decreases it can lead to bradycardia and heartblock.

The most common symptoms of digoxin perniciousness are: slap-upnausea, vomiting, abdominal pain, lethargy, bradycardia Chronicbradycardia, malaise, nausea, anorexia, delirium, vision changes mischievousbradycardia, heartblock, vomiting, shock, hyperkalemia If potassium level is > 5mEq/L with symptomatic bradycardia, digoxin toxicity should be hardened with Digoxin Immune Fab, which works by binding digoxin molecules and helps to eliminate them from the body. Eac h vial of DIGIBIND forget bind with 0.5mg o! f digoxin. References: Micromedex dose cultivation App Thomson Reuters Goodman and Gilmans DIGIBIND Drug Information Leaflet McGraw Hill Diagnosis and TreatmentIf you privation to get a full essay, order it on our website: OrderEssay.net

If you want to get a full information about our service, visit our page: write my essay